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1

HIV-1 Tat Inhibits the 20 S Proteasome and Its 11 S Regulator-mediated Activation

Seeger, Michael, Ferrell, Katherine, Frank, Rainer, Dubiel, Wolfgang

Journal:

Journal of Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 281 KB

english, 1997

2

Cullin 3-Based Ubiquitin Ligases as Master Regulators of Mammalian Cell Differentiation

Dubiel, Wolfgang, Dubiel, Dawadschargal, Wolf, Dieter A., Naumann, Michael

Journal:

Trends in Biochemical Sciences

Year:

2017

Language:

english

File:

PDF, 1.65 MB

english, 2017

3

Phosphorylation by COP9 Signalosome-Associated CK2 Promotes Degradation of p27 during the G1 Cell Cycle Phase

Xiaohua Huang, Erika Wagner, Renate Dumdey, Andreas Peth, Matthias Berse, Wolfgang Dubiel, Christoph Berndt

Journal:

Israel Journal of Chemistry

Year:

2006

Language:

english

File:

PDF, 791 KB

english, 2006

4

Deregulation of the COP9 signalosome–cullin-RING ubiquitin-ligase pathway: Mechanisms and roles in urological cancers

Gummlich, Linda, Rabien, Anja, Jung, Klaus, Dubiel, Wolfgang

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2013

Language:

english

File:

PDF, 1.70 MB

english, 2013

5

Control of Multicellular Development by the Physically Interacting Deneddylases DEN1/DenA and COP9 Signalosome

Christmann, Martin, Schmaler, Tilo, Gordon, Colin, Huang, Xiaohua, Bayram, Özgür, Schinke, Josua, Stumpf, Sina, Dubiel, Wolfgang, Braus, Gerhard H., Heitman, Joseph

Journal:

Year:

2013

Language:

english

File:

PDF, 7.10 MB

english, 2013

6

Optimization of the ion-pair high-performance liquid chromatographic separation of purine derivatives in erythrocytes, thymocytes and liver mitochondria

Ruslan T. Toguzov, Yurii V. Tikhonov, Alexander M. Pimenov, Vadim Yu. Prokudin, Wolfgang Dubiel, Mathias Ziegler, Gerhard Gerber

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1988

Language:

english

File:

PDF, 352 KB

english, 1988

7

A mathematical model to study short-term regulation of mitochondrial energy transduction

Hermann-Georg Holzhütter, Wolfgang Henke, Wolfgang Dubiel, Gerhard Gerber

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

1985

Language:

english

File:

PDF, 1.14 MB

english, 1985

8

Bariatric Surgery Significantly Reduces Serum Concentration of Vascular Endothelial Growth Factor A and Increases Apelin-12 in Patients with Morbid Obesity

Weidlich, Matthias, Huang, Xiaohua, Pratschke, Johann, Dubiel, Wolfgang, Ordemann, Jürgen

Journal:

Bariatric Surgical Patient Care

Year:

2017

Language:

english

File:

PDF, 214 KB

english, 2017

9

Dose-dependent role of novel agents emodin and BTB14431 in colonic cancer treatment in rats

Braumann, Chris, Koplin, Gerold, Geier, Caroline, Höhn, Philipp, Pohlenz, Jana, Dubiel, Wolfgang, Rogalla, Stephan

Journal:

Acta Chirurgica Belgica

Year:

2017

Language:

english

File:

PDF, 1.83 MB

english, 2017

10

Novel Anti-Angiogenic Compounds for Application in Tumor Therapy – COP9 Signalosome-Associated Kinases as Possible Targets

Braumann, Chris, Tangermann, Judith, Jacobi, Christoph, Muller, Joachim, Dubiel, Wolfgang

Journal:

Mini Reviews in Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 223 KB

english, 2008

11

Application of ion-pair high-performance liquid chromatography with radioisotope detection to in vitro studies of nucleoside metabolism in mitochondria

Mathias Ziegler, Wolfgang Dubiel, Wolfgang Henke, Gerhard Gerber, Alexander M. Pimenov, Yurii V. Tikhonov, Ruslan T. Toguzov

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1991

Language:

english

File:

PDF, 223 KB

english, 1991

12

Ubiquitin pathway: Another link in the polyubiquitin chain?

Wolfgang Dubiel, Colin Gordon

Journal:

Current Biology

Year:

1999

Language:

english

File:

PDF, 44 KB

english, 1999

13

Electron microscopy and in vitro deneddylation reveal similar architectures and biochemistry of isolated human and Flag-mouse COP9 signalosome complexes

Rockel, Beate, Schmaler, Tilo, Huang, Xiaohua, Dubiel, Wolfgang

Journal:

Biochemical and Biophysical Research Communications

Year:

2014

Language:

english

File:

PDF, 1.44 MB

english, 2014

14

PBPC mobilization with paclitaxel, ifosfamide, and G-CSF with or without amifostine: results of a prospective randomized trial

Oliver Rick, Nimrod Schwella, Jörg Beyer, Mark Dubiel, Andreas Krusch, Martin Hildebrandt, Jan Schleicher, Stefan Serke, Wolfgang Siegert

Journal:

Transfusion (Wiley)

Year:

2001

Language:

english

File:

PDF, 74 KB

english, 2001

15

Peptide sequencing identifies MSS1, a modulator of HIV Tat-mediated transactivation, as subunit 7 of the 26 S protease

Wolfgang Dubiel, Katherine Ferrell, Martin Rechsteiner

Journal:

Year:

1993

Language:

english

File:

PDF, 376 KB

english, 1993

16

Ubiquitin-dependent Degradation of Id1 and Id3 is Mediated by the COP9 Signalosome

Matthias Berse, Mangkey Bounpheng, Xiaohua Huang, Barbara Christy, Christian Pollmann, Wolfgang Dubiel

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 406 KB

english, 2004

17

The COP9 signalosome-cyclosome connection

Dubiel, Wolfgang

Journal:

Year:

2009

Language:

english

File:

PDF, 883 KB

english, 2009

18

Molecular cloning and expression of subunit 12: a non-MCP and non-ATPase subunit of the 26 S protease

Wolfgang Dubiel, Katherine Ferrell, Renate Dumdey, Sybille Standera, Siegfried Prehn, Martin Rechsteiner

Journal:

Year:

1995

Language:

english

File:

PDF, 541 KB

english, 1995

19

Post-Transcriptional Fine-tuning of COP9 Signalosome Subunit Biosynthesis is Regulated by the c-Myc/Lin28B/let-7 Pathway

Ulrike Leppert, Wolfgang Henke, Xiaohua Huang, Joachim M. Müller, Wolfgang Dubiel

Journal:

Journal of Molecular Biology

Year:

2011

Language:

english

File:

PDF, 1.13 MB

english, 2011

20

Resolving the CSN and CAND1 Paradoxes

Wolfgang Dubiel

Journal:

Year:

2009

Language:

english

File:

PDF, 167 KB

english, 2009

21

The RTP Site Shared by the HIV-1 Tat Protein and the 11 S Regulator Subunit α is Crucial for their Effects on Proteasome Function Including Antigen Processing

Xiaohua Huang, Ulrike Seifert, Ulrike Salzmann, Peter Henklein, Robert Preissner, Wolfgang Henke, Alice J. Sijts, Peter-Michael Kloetzel, Wolfgang Dubiel

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 1.49 MB

english, 2002

22

Hemizygosity for the COP9 signalosome subunit gene,SGN3, in the Smith-Magenis syndrome

Elsea, Sarah H., Mykytyn, Kirk, Ferrell, Katherine, Coulter, Kathryn L., Das, Parimal, Dubiel, Wolfgang, Patel, Pragna I., Metherall, James E.

Journal:

American Journal of Medical Genetics

Year:

1999

Language:

english

File:

PDF, 407 KB

english, 1999

23

The 26S proteasome: a dynamic structure

Michael Seeger, Katherine Ferrell, Wolfgang Dubiel*

Journal:

Molecular Biology Reports

Year:

1997

Language:

english

File:

PDF, 729 KB

english, 1997

24

COP9 signalosome function in the DDR

Ronny Hannß, Wolfgang Dubiel

Journal:

Year:

2011

Language:

english

File:

PDF, 434 KB

english, 2011

25

Determination and Characteristics of Energy-Dependent Proteolysis in Rabbit Reticulocytes

Marianne MÜLLER, Wolfgang DUBIEL, Jörg RATHMANN, Samuel RAPOPORT

Journal:

Year:

1980

Language:

english

File:

PDF, 521 KB

english, 1980

26

CAND1 exchange factor promotes Keap1 integration into cullin 3-RING ubiquitin ligase during adipogenesis

Dubiel, Dawadschargal, Ordemann, Jürgen, Pratschke, Johann, Dubiel, Wolfgang, Naumann, Michael

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2015

Language:

english

File:

PDF, 1.55 MB

english, 2015

27

The ubiquitin- and proteasome-dependent degradation of COX-2 is regulated by the COP9 signalosome and differentially influenced by coxibs

Heiko Neuss, Xiaohua Huang, Bettina K. J. Hetfeld, Rupal Deva, Petra Henklein, Santosh Nigam, Julian W. Mall, Wolfgang Schwenk, Wolfgang Dubiel

Journal:

Journal of Molecular Medicine

Year:

2007

Language:

english

File:

PDF, 490 KB

english, 2007

28

Liver metastases after colonic carcinoma—palliative chemotherapy plus curcumin

Chris Braumann, Nina Guenther, Luisa Mantovani Loeffler, Wolfgang Dubiel

Journal:

International Journal of Colorectal Disease

Year:

2009

Language:

english

File:

PDF, 49 KB

english, 2009

29

The Zinc Finger of the CSN-Associated Deubiquitinating Enzyme USP15 Is Essential to Rescue the E3 Ligase Rbx1

Bettina K.J. Hetfeld, Annett Helfrich, Barbara Kapelari, Hartmut Scheel, Kay Hofmann, Adi Guterman, Michael Glickman, Rüdiger Schade, Peter-Michael Kloetzel, Wolfgang Dubiel

Journal:

Current Biology

Year:

2005

Language:

english

File:

PDF, 264 KB

english, 2005

30

CAND1-dependent control of cullin 1-RING Ub ligases is essential for adipogenesis

Dubiel, Dawadschargal, Gierisch, Maria Elka, Huang, Xiaohua, Dubiel, Wolfgang, Naumann, Michael

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2013

Language:

english

File:

PDF, 1.21 MB

english, 2013

31

Novel curcumin- and emodin-related compounds identified byin silico2D/3D conformer screening induce apoptosis in tumor cells

Melanie Füllbeck, Xiaohua Huang, Renate Dumdey, Cornelius Frommel, Wolfgang Dubiel, Robert Preissner

Journal:

Year:

2005

Language:

english

File:

PDF, 582 KB

english, 2005

32

Accounting for the ATP-consuming processes in rabbit reticulocytes

Werner SIEMS, Wolfgang DUBIEL, Renate DUMDEY, Marianne MÜLLER, Samuel Mitja RAPOPORT

Journal:

Year:

1984

Language:

english

File:

PDF, 611 KB

english, 1984

33

Consequences of COP9 signalosome and 26S proteasome interaction

Xiaohua Huang, Bettina K. J. Hetfeld, Ulrike Seifert, Thilo Kähne, Peter-Michael Kloetzel, Michael Naumann, Dawadschargal Bech-Otschir, Wolfgang Dubiel

Journal:

Year:

2005

Language:

english

File:

PDF, 288 KB

english, 2005

34

Unified nomenclature for the COP9 signalosome and its subunits: an essential regulator of development

Xing-Wang Deng, Wolfgang Dubiel, Ning Wei, Kay Hofmann, Kirsten Mundt, John Colicelli, Jun-ya Kato, Michael Naumann, Daniel Segal, Michael Seeger, Michael Glickman, Daniel A Chamovitz, Anthony Carr

Journal:

Trends in Genetics

Year:

2000

Language:

english

File:

PDF, 86 KB

english, 2000

35

Ubiquitin pathway: Another link in the polyubiquitin chain?

Wolfgang Dubiel, Colin Gordon

Journal:

Current Biology

Year:

1999

Language:

english

File:

PDF, 61 KB

english, 1999

36

Fission Yeast COP9/Signalosome Suppresses Cullin Activity through Recruitment of the Deubiquitylating Enzyme Ubp12p

Chunshui Zhou, Susan Wee, Edward Rhee, Michael Naumann, Wolfgang Dubiel, Dieter A Wolf

Journal:

Year:

2003

Language:

english

File:

PDF, 546 KB

english, 2003

37

Can hyperthermic intraperitoneal chemotherapy efficiency be improved by blocking the DNA repair factor COP9 signalosome?

Feist, Mathilde, Huang, Xiaohua, Müller, Joachim M., Rau, Beate, Dubiel, Wolfgang

Journal:

International Journal of Colorectal Disease

Year:

2014

Language:

english

File:

PDF, 1.71 MB

english, 2014

38

Subunits of the regulatory complex of the 26S protease

Wolfgang Dubiel, Katherine Ferrell, Martin Rechsteiner

Journal:

Molecular Biology Reports

Year:

1995

Language:

english

File:

PDF, 702 KB

english, 1995

39

Cul3 neddylation is crucial for gradual lipid droplet formation during adipogenesis

Dubiel, Dawadschargal, Bintig, Willem, Kähne, Thilo, Dubiel, Wolfgang, Naumann, Michael

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2017

Language:

english

File:

PDF, 1.17 MB

english, 2017

40

Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stability

Andreas Peth, Christoph Berndt, Wolfgang Henke, Wolfgang Dubiel

Journal:

BMC Biochemistry

Year:

2007

Language:

english

File:

PDF, 1.06 MB

english, 2007

41

The COP9 Signalosome Mediates β-Catenin Degradation by Deneddylation and Blocks Adenomatous Polyposis coli Destruction via USP15

Xiaohua Huang, Corinna Langelotz, Bettina K.J. Hetfeld-Pěchoč, Wolfgang Schwenk, Wolfgang Dubiel

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 1.25 MB

english, 2009

42

The COP9 Signalosome: A Multi-DUB Complex

Dubiel, Wolfgang, Chaithongyot, Supattra, Dubiel, Dawadschargal, Naumann, Michael

Journal:

Year:

2020

File:

PDF, 648 KB

2020

43

Conservation of the COP9/signalosome in budding yeast

Susan Wee, Bettina Hetfeld, Wolfgang Dubiel, Dieter A Wolf

Journal:

Year:

2002

Language:

english

File:

PDF, 1.38 MB

english, 2002

44

Exposing the subunit diversity within protein complexes: A mass spectrometry approach

Rozen, Shelly, Tieri, Alessandra, Ridner, Gabriela, Stark, Ann-Kathrin, Schmaler, Tilo, Ben-Nissan, Gili, Dubiel, Wolfgang, Sharon, Michal

Journal:

Year:

2013

Language:

english

File:

PDF, 1.74 MB

english, 2013

45

Diversity of COP9 signalosome structures and functional consequences

Dubiel, Dawadschargal, Rockel, Beate, Naumann, Michael, Dubiel, Wolfgang

Journal:

Year:

2015

Language:

english

File:

PDF, 1.50 MB

english, 2015

46

A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits

Seeger, Michael, Kraft, Regine, Ferrell, Katherine, Bech-Otschir, Dawadschargal, Dumdey, Renate, Schade, Rüdiger, Gordon, Colin, Naumann, Michael, Dubiel, Wolfgang

Journal:

The FASEB Journal

Year:

1998

Language:

english

File:

PDF, 431 KB

english, 1998

47

Electron microscopy and subunit-subunit interaction studies reveal a first architecture of COP9 signalosome

Barbara Kapelari, Dawadschargal Bech-Otschir, Reiner Hegerl, Rüdiger Schade, Renate Dumdey, Wolfgang Dubiel

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 390 KB

english, 2000

48

Caspase Activation Inhibits Proteasome Function during Apoptosis

Xiao-Ming Sun, Michael Butterworth, Marion MacFarlane, Wolfgang Dubiel, Aaron Ciechanover, Gerald M Cohen

Journal:

Year:

2004

Language:

english

File:

PDF, 609 KB

english, 2004

49

[Advances in Molecular and Cell Biology] Intracellular Protein Decradation Volume 27 || The 19S Regulatory Complex of the 26S Proteasome

Dubiel, Wolfgang

Year:

1998

Language:

english

File:

PDF, 2.14 MB

english, 1998

50

The tumor-suppressive reagent taurolidine is an inhibitor of protein biosynthesis

Chris Braumann, Wolfgang Henke, Christoph A. Jacobi, Wolfgang Dubiel

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 201 KB

english, 2004

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